90 Miles From Tyranny

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Wednesday, August 24, 2022

Visage à trois #427

Three Videos For Your Viewing Pleasure:




Three Additional Bonus Videos:

Quick Hits Of Wisdom, Knowledge And Snark #610

 













Quick Hits Of Wisdom, Knowledge And Snark #609


The Antitumor Effects of Quercetin

  • Quercetin has an apoptotic effect on aging cells that may help prevent or be helpful in the treatment of cancer; years of research have also demonstrated it prevents chemically induced cancer and lung cancer, and inhibits the proliferation of cancer cells
  • Quercetin has also demonstrated the ability to mitigate some of the effects of sleep deprivation, including mood changes, anxiety, memory performance, hyperactivity and cognitive impairment
  • The combination of quercetin, bromelain, vitamin C and zinc has emerged in at least two of the successful protocols used to treat COVID-19; historically, data have shown it is effective against influenza, zika, hepatitis B and rhinovirus responsible for the common cold
  • Quercetin is not water-soluble and is poorly absorbed unless it is paired with bromelain or vitamin C. Quercetin has shown positive benefits for heart disease, high blood pressure, metabolic syndrome, NAFLD and arthritis
  • Quercetin is found in onions, red grapes and green tea. 
It could be a useful supplement to stock in your medicine chest to use when you believe you may be getting an upper respiratory infection
Quercetin is an antioxidant flavonol that's found in foods such as red grapes, green tea, elderflower and onions, to name a few.1 As the health benefits of the supplement become more widely known, the market has grown rapidly.2 According to market research, quercetin market was worth $261.12 million in 2020 and is expected to reach $406.58 million in 2027.

Quercetin has a wide range of benefits, which has made it useful for a variety of different health conditions. In the last two years, the antiviral benefits of quercetin have been the focus of many studies.3 However, there are other, lesser-known benefits, including the effects as a senolytic agent against senescence-mediated cancer growth.4
It is perhaps most well-known as a strong antioxidant5 and antiviral.6 For example, Elderflower extract, which is rich in quercetin, is a traditional tonic used to boost immunity. In supplement form, quercetin has been used to prevent and treat the common cold and influenza.
7

According to Mount Sinai,8 quercetin should be used with caution as it may interact with certain antibiotics by reducing the effectiveness of the drug. It may also enhance the effect of some blood thinners, which can increase your risk of bleeding. In addition to these, it may interact with corticosteroids, digoxin, cyclosporine and fluoroquinolones.

Quercetin Effect on Senescence-Mediated Cancer Cells
A paper9 published in August 2022 in Nutrition Research analyzed the pro-apoptotic effect that quercetin has on aging cells. The paper reviewed preclinical and early phase data using quercetin as a senolytic agent and found the data showed it was effective in “preventing or alleviating cancer formation.”

The authors reviewed the importance of cellular aging in the development of cancer cells and the effect that quercetin may have on the suppression of cancer cell proliferation. Research has found that cellular aging can suppress tumor development, but paradoxically can also enhance cancer development.10

Cellular senescence is a dynamic and multi-step process that is associated with alterations in metabolic activity and gene expression.11 This can compromise tissue regeneration and contribute to aging. On the other hand, by removing senescent cells, age-related dysfunction can be attenuated and potentially extend the lifespan.

One paper12 published in 2008 recognized that animal studies had demonstrated quercetin could prevent chemically-induced cancer growth and epidemiological studies found it was associated with preventing lung cancer. One study13 focused on the effect that physiologically attainable doses of quercetin had on the inhibition of cancer cell proliferation. The researchers believed their study demonstrated quercetin had chemopreventive properties.

Lab studies14 have also demonstrated that quercetin is a strong antioxidant and has pro-apoptotic effects on tumor cells, with the ability to block growth at different phases of the cell cycle. Research15 also has demonstrated that quercetin can promote the loss of cell viability and autophagy through several pathways, including those involving mitochondrial function and glucose metabolism.

Data16 indicate that quercetin could play a role in cancer treatment as it reportedly has synergistic effects in combination with chemotherapy agents or radiation therapy. Quercetin has also shown promising results with chemoprotective and radioprotective properties, by protecting normal cells against the effects of chemotherapy and radiation therapy.

One paper17 identified some of the anti-inflammatory, antioxidant and antiproliferative properties quercetin has that enhances breast cancer treatment, while another18 evaluated its effect on the treatment of ovarian cancer, which is a serious cancer growth and threat to...

Morning Mistress

The 90 Miles Mystery Video: Nyctophilia Edition #1120


Before You Click On The "Read More" Link, 

Please Only Do So If You Are Over 21 Years Old.

If You are Easily Upset, Triggered Or Offended, This Is Not The Place For You.  

Please Leave Silently Into The Night......

The 90 Miles Mystery Box: Episode #1820

You have come across a mystery box. But what is inside? 
It could be literally anything from the serene to the horrific, 
from the beautiful to the repugnant, 
from the mysterious to the familiar.

If you decide to open it, you could be disappointed, 
you could be inspired, you could be appalled. 

This is not for the faint of heart or the easily offended. 
You have been warned.

Hot Pick Of The Late Night

 


Tuesday, August 23, 2022

Girls With Guns

Visage à trois #426

Three Videos For Your Viewing Pleasure:




Three Additional Bonus Videos:

Quick Hits Of Wisdom, Knowledge And Snark #609

 











Quick Hits Of Wisdom, Knowledge And Snark #608

Report: Documents Show Biden White House Involvement in Trump Criminal Probe


Joe Biden’s White House was intimately involved in the Department of Justice’s (DOJ) criminal probe into former President Donald Trump, according to government documents reviewed by Just The News.

Several correspondences between Trump’s attorneys and members of the Biden administration revealed that the federal government appeared poised to waive Trump’s claims of executive privilege over documents that Trump kept at Mar-a-Lago until earlier this year.

As Just The News reported:

The memos show then-White House Deputy Counsel Jonathan Su was engaged in conversations with the FBI, DOJ and National Archives as early as April, shortly after 15 boxes of classified and other materials were voluntarily returned to the federal historical agency from Trump’s Florida home.

By May, Su conveyed to the Archives that President Joe Biden would not object to waiving his predecessor’s claims to executive privilege, a decision that opened the door for DOJ to get a grand jury to issue a subpoena compelling Trump to turn over any remaining materials he possessed from his presidency.

A May 10 letter from acting National Archivist Debra Steidel Wall to Trump’s legal team confirmed the White House’s involvement in the DOJ probe against Trump.

“On April 11, 2022, the White House Counsel’s Office — affirming a request from the Department of Justice supported by an FBI letterhead memorandum — formally transmitted a request that NARA provide the FBI access to the 15 boxes for its review within seven days, with the possibility that the FBI might request copies of specific documents following its review of the boxes,” Wall wrote.

The letter continued:
The Counsel to the President has informed me that, in light of the particular circumstances presented here, President Biden defers to my determination, in consultation with the Assistant Attorney General for the Office of Legal Counsel, regarding whether or not I should uphold the former President’s purported “protective assertion of executive privilege.”…I have therefore decided not to honor the former President’s “protective” claim of privilege.
These documents reviewed by Just The News are the strongest pieces of evidence showing the Biden White House’s involvement in the DOJ probe, although the White House previously claimed to have “no advanced knowledge” of the recent FBI raid on Mar-a-Lago.

“Does ANYBODY really believe that the White House didn’t know about this?” Trump posted on Truth Social. “WITCH HUNT!”

Police direct traffic outside an entrance to former President Donald Trump’s Mar-a-Lago estate, Monday, Aug. 8, 2022, in Palm Beach, FL. Trump said in a lengthy statement that the FBI was conducting a raid of his Mar-a-Lago estate. (AP Photo/Terry Renna)

However, Just the News does not report that the White House had specific knowledge of the search warrant or the raid, but that their participation, through waiving executive privilege, was crucial to the investigation.

In affirming its decision not to honor Trump’s claims of executive privilege, Wall relied on a Supreme Court precedent that “strongly suggests that a former President may not successfully assert executive privilege ‘against the very Executive Branch in whose name the privilege is invoked.'”

However, this case was ruled before Congress’s current Presidential Records Act was enacted, Just The News explained.

Wall’s letter to Trump’s attorneys also claimed the former president had items marked as “classified national security information” in the set of 15 boxes Trump’s team returned to the National Archives in February.

After the National Archives reviewed those documents, they told the DOJ about the potentially classified material, which prompted the DOJ to ask Biden to request the National Archives turn over access of the documents to...

The Trump Warrant Had No Legal Basis


A former president’s rights under the Presidential Records Act trump the statutes the FBI cited to justify the Mar-a-Lago raid.

Was the Federal Bureau of Investigation justified in searching Donald Trump’s residence at Mar-a-Lago? The judge who issued the warrant for Mar-a-Lago has signaled that he is likely to release a redacted version of the affidavit supporting it. But the warrant itself suggests the answer is likely no—the FBI had no legally valid cause for the raid.

The warrant authorized the FBI to seize “all physical documents and records constituting evidence, contraband, fruits of crime, or other items illegally possessed in violation of 18 U.S.C. §§793, 2071, or 1519” (emphasis added). These three criminal statutes all address the possession and handling of materials that contain national-security information, public records or material relevant to an investigation or other matters properly before a federal agency or the courts.

The materials to be seized included “any government and/or Presidential Records created between January 20, 2017, and January 20, 2021”—i.e., during Mr. Trump’s term of office. Virtually all the materials at Mar-a-Lago are likely to fall within this category. Federal law gives Mr. Trump a right of access to them. His possession of them is entirely consistent with that right, and therefore lawful, regardless of the statutes the FBI cites in its warrant.

Those statutes are general in their text and application. But Mr. Trump’s documents are covered by a specific statute, the Presidential Records Act of 1978. It has long been the Supreme Court position, as stated in Morton v. Mancari (1974), that “where there is no clear intention otherwise, a specific statute will not be controlled or nullified by a general one, regardless of the priority of enactment.” The former president’s rights under the PRA trump any application of the laws the FBI warrant cites.

The PRA dramatically changed the rules regarding ownership and treatment of presidential documents. Presidents from George Washington through Jimmy Carter treated their White House papers as their personal property, and neither Congress nor the courts disputed that. In Nixon v. U.S. (1992), the U.S. Circuit Court of Appeals for the District of Columbia held that Richard Nixon had a right to compensation for his presidential papers, which the government had retained under the Presidential Recordings and Materials Preservation Act of 1974 (which applied only to him). “Custom and usage evidences the kind of mutually explicit understandings that are encompassed within the constitutional notion of ‘property’ protected by the Fifth Amendment,” the judges declared.

The PRA became effective in 1981, at the start of Ronald Reagan’s presidency. It established a unique statutory scheme, balancing the needs of the government, former presidents and history. The law declares presidential records to be public property and provides that “the Archivist of the United States shall assume responsibility for the custody, control, and preservation of, and access to, the Presidential records.”

The PRA lays out detailed requirements for how the archivist is to administer the records, handle privilege claims, make the records public, and impose restrictions on access. Notably, it doesn’t address the process by which a former president’s records are physically to be turned over to the archivist, or set any deadline, leaving this matter to be negotiated between the archivist and the former president.

The PRA explicitly guarantees a former president continuing access to his papers. Those papers must ultimately be made public, but in the meantime—unlike with all other government documents, which are available 24/7 to currently serving executive-branch officials—the PRA establishes restrictions on access to a former president’s records, including a five-year restriction on access applicable to...