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Ninety miles from the South Eastern tip of the United States, Liberty has no stead. In order for Liberty to exist and thrive, Tyranny must be identified, recognized, confronted and extinguished.
"First, we found that irisin treatment led to a remarkable reduction of amyloid beta pathology," says Dr. Se Hoon Choi in a media release. "Second, we showed this effect of irisin was attributable to increased neprilysin activity owing to increased levels of neprilysin secreted from cells in the brain called astrocytes..."So, in short, hit the treadmill!
"Our findings indicate that irisin is a major mediator of exercise-induced increases in neprilysin levels leading to reduced amyloid beta burden, suggesting a new target pathway for therapies aimed at the prevention and treatment of Alzheimer's disease," says Rudolph Tanzi, PhD, a senior author of the study and director of the Genetics and Aging Research Unit.